Patch 2.2 is on the PTR currently, and there are some fairly substantial changes being made to several core functions for certain Addons. Most notably there will be issues with Addons which take advantage of tooltip functions, such as bag mods, spell/skill info mods, etc.
With this in mind, we've preemptively added a 2.2.0 game version to our database. Please feel free to upload your 2.2.0 compatible Addons and flag them for this game version.
For anyone curious about the changes being made in 2.2.0, there's a great list compiled by Iriel - a Community MVP on the official forums. You can check them out in the Upcoming 2.2 Changes - Concise List thread.